Roles of the C. elegans cyclophilin-like protein MOG-6 in MEP-1 binding and germline fates.

@article{Belfiore2004RolesOT,
  title={Roles of the C. elegans cyclophilin-like protein MOG-6 in MEP-1 binding and germline fates.},
  author={M. Stefania Belfiore and Paolo Pugnale and Zarifja Saudan and Alessandro Puoti},
  journal={Development},
  year={2004},
  volume={131 12},
  pages={
          2935-45
        }
}
The switch from spermatogenesis to oogenesis in the Caenorhabditis elegans hermaphrodite requires mog-6, which post-transcriptionally represses the fem-3 RNA. In this study, we show that mog-6 codes for a divergent nuclear cyclophilin, in that a conserved domain is not required for its function in the sperm-oocyte switch. MOG-6 binds to the nuclear zinc finger protein MEP-1 through two separate domains that are essential for the role of MOG-6 in the sperm-oocyte switch. We propose that MOG-6… CONTINUE READING

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On the control of germ cell development in Caenorhabditis elegans

  • B. Kraemer, S. Crittenden, +4 authors M. Wickens
  • Dev . Biol .
  • 1999

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