Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex

@article{Toyoda2009RolesOT,
  title={Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex},
  author={Hiroki Toyoda and Minggao Zhao and Bettina Ulzh{\"o}fer and Long-Jun Wu and Hui Xu and P. H. Seeburg and Rolf Sprengel and Rohini Kuner and Min Zhuo},
  journal={Molecular Pain},
  year={2009},
  volume={5},
  pages={46 - 46}
}
Cortical areas including the anterior cingulate cortex (ACC) are important for pain and pleasure. Recent studies using genetic and physiological approaches have demonstrated that the investigation of basic mechanism for long-term potentiation (LTP) in the ACC may reveal key cellular and molecular mechanisms for chronic pain in the cortex. Glutamate N-methyl D-aspartate (NMDA) receptors in the ACC are critical for the induction of LTP, including both NR2A and NR2B subunits. However, cellular and… CONTINUE READING

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