Roles of reactive oxygen species in the fate of stem cells.

  title={Roles of reactive oxygen species in the fate of stem cells.},
  author={Pooja Chaudhari and Zhaohui Ye and Young Boo Jang},
  journal={Antioxidants & redox signaling},
  volume={20 12},
SIGNIFICANCE Stem cells are characterized by the properties of self-renewal and the ability to differentiate into multiple cell types, and thus maintain tissue homeostasis. Reactive oxygen species (ROS) are a natural byproduct of aerobic metabolism and have roles in cell signaling. Regulation of ROS has a vital role in maintaining "stemness" and differentiation of the stem cells, as well as in progression of stem-cell-associated diseases. RECENT ADVANCES As of late, much research has been… CONTINUE READING
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