Roles of pilin and PilC in adhesion of Neisseria meningitidis to human epithelial and endothelial cells.

@article{Nassif1994RolesOP,
  title={Roles of pilin and PilC in adhesion of Neisseria meningitidis to human epithelial and endothelial cells.},
  author={Xavier Nassif and J. L. Beretti and Jack Lowy and Per Stenberg and Peadar O'Gaora and John M Pfeifer and Staffan J. Normark and Magdalene So},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 9},
  pages={3769-73}
}
Pili and pilin antigenic variation play important roles in adhesion of Neisseria meningitidis (MC) to human epithelial and endothelial cells. We recently identified one pilin variant that confers high adhesiveness of MC to human epithelial cells in culture. However, other factor(s) also play a role in MC adhesiveness, since some nonadhesive variants of MC strain 8013 are piliated and produce the same pilin variant as adhesive derivatives. PilC1 and PilC2, high molecular weight outer membrane… CONTINUE READING
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