Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease

@article{Enomoto2005RolesOO,
  title={Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease},
  author={A. Enomoto and H. Endou},
  journal={Clinical and Experimental Nephrology},
  year={2005},
  volume={9},
  pages={195-205}
}
  • A. Enomoto, H. Endou
  • Published 2005
  • Biology, Medicine
  • Clinical and Experimental Nephrology
  • Renal proximal and distal tubules are highly polarized epithelial cells that carry out the specialized directional transport of various solutes. This renal function, which is essential for homeostasis in the body, is achieved through the close pairing of apical and basolateral carriers expressed in the renal epithelial cells. The family of organic anion transporters (OATs), which belong to the major facilitator superfamily (SLC22A), are expressed in the renal epithelial cells to regulate the… CONTINUE READING
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