Roles of microfilaments in exocytosis: a new hypothesis.

  title={Roles of microfilaments in exocytosis: a new hypothesis.},
  author={Akihisa Segawa and Shohei Yamashina},
  journal={Cell structure and function},
  volume={14 5},
We observed the dynamic changes in the localization of microfilaments during the exocytic secretion of rat parotid and submandibular gland acinar cells, and obtained results which led us to propose a new concept of microfilament function in exocytosis. With the electron microscopy, NBD-Phallacidin (NBD-PL) fluorescence technique and immunohistochemistry for myosin, microfilaments consisting of F-actin and myosin were localized mainly underneath the luminal plasma membrane. Microfilaments were… CONTINUE READING


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