Roles of manganese and iron in the regulation of the biosynthesis of manganese-superoxide dismutase in Escherichia coli.

@article{Hassan1994RolesOM,
  title={Roles of manganese and iron in the regulation of the biosynthesis of manganese-superoxide dismutase in Escherichia coli.},
  author={Hosni M. Hassan and Laura W. Schrum},
  journal={FEMS microbiology reviews},
  year={1994},
  volume={14 4},
  pages={
          315-23
        }
}
Aerobic life-style offers both benefits and risks to living cells. The major risk comes from the formation of reactive oxygen intermediates (i.e. superoxide radical, O2-; hydrogen peroxide, H2O2; and hydroxyl radical, OH.) during normal oxygen metabolism. However, living cells are able to cope with oxygen toxicity by virtue of a unique set of antioxidant enzymes that scavenge O2- and H2O2, and prevent the formation OH.. Superoxide dismutases (SODs; EC 1.15.1.1) are metalloenzymes essential for… CONTINUE READING

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