Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility

Abstract

Type 2 diabetes usually ensues from the inability of pancreatic beta cells to compensate for incipient insulin resistance. The loss of beta cell mass, function, and potentially beta cell identity contribute to this dysfunction to extents which are debated. In recent years, long non-coding RNAs (lncRNAs) have emerged as potentially providing a novel level of… (More)
DOI: 10.3389/fgene.2014.00193

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