Roles of lipooligosaccharide and capsular polysaccharide in antimicrobial resistance and natural transformation of Campylobacter jejuni.

@article{Jeon2009RolesOL,
  title={Roles of lipooligosaccharide and capsular polysaccharide in antimicrobial resistance and natural transformation of Campylobacter jejuni.},
  author={Byeonghwa Jeon and Wayne T. Muraoka and Alexandra J Scupham and Qijing Zhang},
  journal={The Journal of antimicrobial chemotherapy},
  year={2009},
  volume={63 3},
  pages={462-8}
}
OBJECTIVES This study is aimed to determine the role of capsular polysaccharide (CPS) and lipooligosaccharide (LOS) in modulating antimicrobial resistance and natural transformation of Campylobacter jejuni, an important food-borne human pathogen. METHODS A series of C. jejuni mutants, which are defective in either CPS or LOS or both, were constructed. The antimicrobial susceptibility, bacterial surface hydrophobicity, natural transformation frequency and DNA binding and uptake were measured… CONTINUE READING

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