Roles of hippocampal GABAA and muscarinic receptors in consolidation of context memory and context–shock association in contextual fear conditioning: A double dissociation study

@article{Chang2012RolesOH,
  title={Roles of hippocampal GABAA and muscarinic receptors in consolidation of context memory and context–shock association in contextual fear conditioning: A double dissociation study},
  author={Shih-Dar Chang and K. C. Liang},
  journal={Neurobiology of Learning and Memory},
  year={2012},
  volume={98},
  pages={17-24}
}
Contextual fear conditioning involves forming a context representation and associating it to a shock, both of which involved the dorsal hippocampus (DH) according to our recent findings. This study tested further whether the two processes may rely on different neurotransmitter systems in the DH. Male Wistar rats with cannula implanted into the DH were subjected to a two-phase training paradigm of contextual fear conditioning to separate context learning from context-shock association in two… CONTINUE READING

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