Roles of hepatocyte growth factor and its receptor Met during gastric ulcer healing in rats.

@article{Schmassmann1997RolesOH,
  title={Roles of hepatocyte growth factor and its receptor Met during gastric ulcer healing in rats.},
  author={Adrian Schmassmann and C Stettler and Richard Poulsom and Nadya Tarasova and Claudia Hirschi and Beatrice Flogerzi and Kunio Matsumoto and Toru Nakamura and Fred Halter},
  journal={Gastroenterology},
  year={1997},
  volume={113 6},
  pages={1858-72}
}
BACKGROUND & AIMS It is unclear which growth factors are primarily responsible for stimulating gastric ulcer healing. The roles of hepatocyte growth factor (HGF) and Met/HGF receptor during gastric ulcer healing were studied in rats. METHODS HGF and Met/HGF receptor were located and quantified by in situ hybridization and immunohistochemistry during experimental gastric ulcer healing. The in vivo effects of exogenous recombinant human HGF on cell proliferation and ulcer healing were assessed… CONTINUE READING