Roles of genetic variations in signalling/immunoregulatory molecules in susceptibility to systemic lupus erythematosus.

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a complex genetic basis that includes many susceptibility genes on multiple chromosomes. As complex human diseases like SLE involve multiple, interacting genetic and environmental determinants, identifying genes for complex traits is challenging and has had limited success so far… (More)

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