Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury.

  title={Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury.},
  author={Emanuela Esposito and Marika Cordaro and Salvatore Cuzzocrea},
  journal={Pharmacological research},
Ethanolamides of long-chain fatty acids are a class of endogenous lipid mediators generally referred to as N-acylethanolamines (NAEs). NAEs include anti-inflammatory and analgesic palmitoylethanolamide, anorexic oleoylethanolamide, stearoylethanolamide, and the endocannabinoid anandamide. Traumatic brain injury (TBI), associated with a high morbidity and mortality and no specific therapeutic treatment, has become a pressing public health and medical problem. TBI is a complex process evoking… CONTINUE READING
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