Roles of estrogen receptors alpha and beta in differentiation of mouse sexual behavior.

@article{Kudwa2006RolesOE,
  title={Roles of estrogen receptors alpha and beta in differentiation of mouse sexual behavior.},
  author={Andrea E. Kudwa and Vasiliki J. Michopoulos and Jessica Gatewood and Emilie F. Rissman},
  journal={Neuroscience},
  year={2006},
  volume={138 3},
  pages={921-8}
}
Sex differences in brain and behavior are ubiquitous in sexually reproducing species. Developmental differences in circulating concentrations of gonadal steroids underlie many sexual dimorphisms. During the late embryonic and early perinatal periods, the testes produce androgens, thus, male brains are exposed to testosterone, and in situ testosterone is aromatized to estradiol. In contrast, females are not exposed to high concentrations of testosterone or estradiol until puberty. In many… CONTINUE READING

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