Roles of cis- and trans-changes in the regulatory evolution of genes in the gluconeogenic pathway in yeast.

@article{Chang2008RolesOC,
  title={Roles of cis- and trans-changes in the regulatory evolution of genes in the gluconeogenic pathway in yeast.},
  author={Ya-Wen Chang and Fu-Guo Robert Liu and Ning Yu and Huang-Mo Sung and Peggy H Yang and Daryi Wang and C N Huang and Ming-Che Shih and Wen-Hsiung Li},
  journal={Molecular biology and evolution},
  year={2008},
  volume={25 9},
  pages={1863-75}
}
The yeast Saccharomyces cerevisiae proliferates rapidly in glucose-containing media. As glucose is getting depleted, yeast cells enter the transition from fermentative to nonfermentative metabolism, known as the diauxic shift, which is associated with major changes in gene expression. To understand the expression evolution of genes involved in the diauxic shift and in nonfermentative metabolism within species, a laboratory strain (BY), a wild strain (RM), and a clinical isolate (YJM) were used… CONTINUE READING
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