Roles of cell adhesion molecules nectin and nectin-like molecule-5 in the regulation of cell movement and proliferation.

@article{Ogita2008RolesOC,
  title={Roles of cell adhesion molecules nectin and nectin-like molecule-5 in the regulation of cell movement and proliferation.},
  author={Hisakazu Ogita and Wataru Ikeda and Yoshimi Takai},
  journal={Journal of microscopy},
  year={2008},
  volume={231 3},
  pages={455-65}
}
In response to chemoattractants, migrating cells form protrusions, such as lamellipodia and filopodia, and structures, such as ruffles over lamellipodia, focal complexes and focal adhesions at leading edges. The formation of these leading edge structures is essential for directional cell movement. Nectin-like molecule-5 (Necl-5) interacts in cis with PDGF… CONTINUE READING