Roles of autophagy in HIV infection.

  title={Roles of autophagy in HIV infection.},
  author={Christina Dinkins and Manohar Pilli and John H Kehrl},
  journal={Immunology and cell biology},
  volume={93 1},
Autophagy is a major cellular pathway, which at basal levels regulates and maintains the cytoplasmic environment through the capture, isolation and digestion of intracellular materials in a specialized structure called an autophagosome. The unique ability of autophagy to degrade large targets, such as damaged and surplus organelles, intracellular microbes and protein aggregates, has made it a prime focus in inflammation and microbial research. Indeed, autophagy has been shown to be involved in… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 17 extracted citations


Publications referenced by this paper.
Showing 1-10 of 224 references

The cytoplasmic body component TRIM5alpha restricts HIV1 infection in Old World monkeys

  • M Stremlau
  • Nature,
  • 2004
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…