Roles of TNF-α and IgE in the late phase of contact hypersensitivity induced by trimellitic anhydride

Abstract

Trimellitic anhydride (TMA) is widely used industrially to make epoxy and alkyd resins, plasticizers and surfactants. The purpose of this study was to investigate whether contact hypersensitivity (CHS) is induced by repeated TMA challenge and the role of TNF-a and IgE in the TMA-induced CHS. The repetition of the challenge enlarged the extent of an early… (More)
DOI: 10.1038/emm.2005.51

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