Roles of Pro- and Anti-Inflammatory Cytokines in the Pathogenesis of SLE

Abstract

SLE is an autoimmune inflammatory disease in which various pro- and anti-inflammatory cytokines, including TGF-β, IL-10, BAFF, IL-6, IFN-α, IFN-γ, IL-17, and IL-23, play crucial pathogenic roles. Virtually, all these cytokines can be generated by both innate and adaptive immune cells and exert different effects depending on specific local microenvironment… (More)
DOI: 10.1155/2012/347141

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