Roles of MMP/TIMP in regulating matrix swelling and cell migration during chick corneal development.

@article{Huh2007RolesOM,
  title={Roles of MMP/TIMP in regulating matrix swelling and cell migration during chick corneal development.},
  author={Man-Il Huh and Young-mi Lee and Seong-Kyung Seo and Bong-Seok Kang and Yongmin Chang and Young-Sup Lee and Mary Elizabeth Fini and S Kang and Jae-Chang Jung},
  journal={Journal of cellular biochemistry},
  year={2007},
  volume={101 5},
  pages={1222-37}
}
Tissue remodeling is central to embryonic development. Here, we used immunohistochemistry, Western blotting, and RT-PCR analysis to investigate the roles of matrix metalloproteinases (MMPs) and the related "a disintegrin and metalloproteinase" (ADAM) family proteinases in chick corneal development. While MMP-13 was expressed in developing chick corneas from embryonic day (ED) 5 to ED 10, its inhibitor, tissue inhibitors of metalloproteinase-1 (TIMP-1), was expressed from ED 18 to 2 days post… CONTINUE READING
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