Roles of K+ and Cl- channels in cAMP-induced pulmonary vasodilation.

Abstract

Increase in intracellular adenosine 3', 5'-cyclic monophosphate (cAMP) is a common pathway for many clinically used drugs to cause pulmonary artery (PA) relaxation. Activity of sarcolemmal K+ and Cl(-)-channels is an important determinant of membrane potential (Em), which, in turn, plays a critical role in regulating pulmonary vascular tone. Whether K+ and… (More)

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Cite this paper

@article{Zhao1998RolesOK, title={Roles of K+ and Cl- channels in cAMP-induced pulmonary vasodilation.}, author={Y-J Zhao and J Wang and L J. Rubin and X J Yuan}, journal={Experimental lung research}, year={1998}, volume={24 1}, pages={71-83} }