Roles of HIF-1α, VEGF, and NF-κB in Ischemic Preconditioning-Mediated Neuroprotection of Hippocampal CA1 Pyramidal Neurons Against a Subsequent Transient Cerebral Ischemia

Abstract

Ischemic preconditioning (IPC) provides neuroprotection against subsequent severe ischemic insults by specific mechanisms. We tested the hypothesis that IPC attenuates post-ischemic neuronal death in the gerbil hippocampal CA1 region (CA1) throughout hypoxia inducible factor-1α (HIF-1α) and its associated factors such as vascular endothelial growth factor… (More)
DOI: 10.1007/s12035-016-0219-2

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@article{Lee2016RolesOH, title={Roles of HIF-1α, VEGF, and NF-κB in Ischemic Preconditioning-Mediated Neuroprotection of Hippocampal CA1 Pyramidal Neurons Against a Subsequent Transient Cerebral Ischemia}, author={Jae-chul Lee and Hyun-Jin Tae and In Hye Kim and Jeong Hwi Cho and Tae-Kyeong Lee and Joon Ha Park and Ji Hyeon Ahn and Soo Young Choi and Hui Chen Bai and Bich-Na Shin and Geum-Sil Cho and Dae Won Kim and Il Jun Kang and Young-Guen Kwon and Young-Myeong Kim and Moo-Ho Won and Eun Joo Bae}, journal={Molecular Neurobiology}, year={2016}, volume={54}, pages={6984-6998} }