Roles of Grainyhead-like transcription factors in cancer


The mammalian homologs of the D. melanogaster Grainyhead gene, Grainyhead-like 1–3 (GRHL1, GRHL2 and GRHL3), are transcription factors implicated in wound healing, tubulogenesis and cancer. Their induced target genes encode diverse epithelial cell adhesion molecules, while mesenchymal genes involved in cell migration and invasion are repressed. Moreover… (More)
DOI: 10.1038/onc.2017.178


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@article{Frisch2017RolesOG, title={Roles of Grainyhead-like transcription factors in cancer}, author={Shelby Frisch and Jacob Farris and Phillip M. Pifer}, journal={Oncogene}, year={2017}, volume={36}, pages={6067-6073} }