Roles of Dicer-Like Proteins 2 and 4 in Intra- and Intercellular Antiviral Silencing.

  title={Roles of Dicer-Like Proteins 2 and 4 in Intra- and Intercellular Antiviral Silencing.},
  author={Cheng Qin and Bin Li and Yaya Fan and Xian Zhang and Zhiming Yu and Eugene V Ryabov and Mei Ping Zhao and Hui Wang and Nong Nong Shi and Pengcheng Zhang and Stephen C. Jackson and Mahmut T{\"o}r and Qi Cheng and Yule Liu and Philippe Gallusci and Yiguo Hong},
  journal={Plant physiology},
  volume={174 2},
RNA silencing is an innate antiviral mechanism conserved in organisms across kingdoms. Such a cellular defense involves DICER or DICER-LIKEs (DCLs) that process plant virus RNAs into viral small interfering RNAs (vsiRNAs). Plants encode four DCLs that play diverse roles in cell-autonomous intracellular virus-induced RNA silencing (known as VIGS) against viral invasion. VIGS can spread between cells. However, the genetic basis and involvement of vsiRNAs in non-cell-autonomous intercellular VIGS… CONTINUE READING

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Respective contributions of Arabidopsis DCL 2 and DCL 4 to RNA silencing

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