Roles of DNA helicases in the mediation and regulation of homologous recombination.


Homologous recombination (HR) is an evolutionarily conserved process that eliminates DNA double-strand breaks from chromosomes, repairs injured DNA replication forks, and helps orchestrate meiotic chromosome segregation. Recent studies have shown that DNA helicases play multifaceted roles in HR mediation and regulation. In particular, the S. cerevisiae Sgs1… (More)
DOI: 10.1007/978-1-4614-5037-5_9


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