Roles of Cdc48 in regulated protein degradation in yeast.

Abstract

The chaperone-related, ubiquitin-selective AAA (ATPase associated with a variety of cellular activities) protein Cdc48 (also known as TER94, p97 and VCP) is a key regulator of intracellular proteolysis in eukaryotes. It uses the energy derived from ATP hydrolysis to segregate ubiquitylated proteins from stable assemblies with proteins, membranes and… (More)
DOI: 10.1007/978-94-007-5940-4_8

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