Roles of CDX2 and EOMES in human induced trophoblast progenitor cells.

@article{Chen2013RolesOC,
  title={Roles of CDX2 and EOMES in human induced trophoblast progenitor cells.},
  author={Yin Chen and Kai Wang and Yun Guo Gong and Sok Kean Khoo and Richard Leach},
  journal={Biochemical and biophysical research communications},
  year={2013},
  volume={431 2},
  pages={197-202}
}
Abnormal trophoblast lineage proliferation and differentiation in early pregnancy have been associated with the pathogenesis of placenta diseases of pregnancy. However, there is still a gap in understanding the molecular mechanisms of early placental development due to the limited primary trophoblast cultures and fidelity of immortalized trophoblast lines. Trophoblasts stem (TS) cells, an in vitro model of trophectoderm that can differentiate into syncytiotrophoblasts and extravillous… CONTINUE READING

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