Roles of CD4+ and CD8+ cells in UVB-induced suppression of splenic alloantigen-presenting function.


Whole body ultraviolet light (UV) radiation causes systemic immunosuppression. Splenic antigen-presenting cell (APC) activity is decreased by UV radiation. To determine whether splenic CD4+ or CD8+ cells are involved in the UV-induced depression of splenic alloantigen-presenting function, we investigated the effect of in vivo UV radiation on the splenic… (More)