Roles of Bone-Marrow-Derived Cells and Inflammatory Cytokines in Neointimal Hyperplasia after Vascular Injury

  title={Roles of Bone-Marrow-Derived Cells and Inflammatory Cytokines in Neointimal Hyperplasia after Vascular Injury},
  author={Makoto Shoji and Shinji Koba and Youichi Kobayashi},
  booktitle={BioMed research international},
Bone-marrow-derived cells can generate vascular progenitor cells that contribute to pathological remodeling in models of restenosis after percutaneous coronary intervention (PCI). We created models of vascular injury in mice with bone marrow transplants (BMT) to determine relationships between bone-marrow-derived cells and subsequent biological factors. Mesenchymal stromal cells (MSCs) seemed to inhibit the inflammatory reaction and help stabilize injured vascular regions through mobilizing… CONTINUE READING
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Publications referenced by this paper.
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Clinical results after coronary stenting with the Genous™ Bio-engineered R stent™: 12-month outcomes of the e-HEALING (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth) worldwide registry.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology • 2011
View 1 Excerpt

Mesenchymal stem cell seeding promotes reendothelialization of the endovascular stent

X.Wu, G.Wang, C. Tang
Journal of Biomedical Materials Research A, vol. 98, no. 3, pp. 442– 449, 2011. • 2011
View 1 Excerpt

Endovascular injury induces rapid phenotypic changes in perivascular adipose tissue.

Arteriosclerosis, thrombosis, and vascular biology • 2010
View 1 Excerpt

Antithrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 1 Excerpt

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