Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli.

We report observations suggesting that the transcription elongation factor NusA promotes a previously unrecognized class of transcription-coupled repair (TCR) in addition to its previously proposed role in recruiting translesion synthesis (TLS) DNA polymerases to gaps encountered during transcription. Earlier, we reported that NusA physically and… CONTINUE READING