Roles for ORC in M phase and S phase.

@article{Dillin1998RolesFO,
  title={Roles for ORC in M phase and S phase.},
  author={Andrew G Dillin and Jasper Rine},
  journal={Science},
  year={1998},
  volume={279 5357},
  pages={1733-7}
}
The origin recognition complex (ORC), a six-subunit protein, functions as the replication initiator in the yeast Saccharomyces cerevisiae. Initiation depends on the assembly of the prereplication complex in late M phase and activation in S phase. One subunit of ORC, Orc5p, was required at G1/S and in early M phase. Asynchronous cells with a temperature… CONTINUE READING