Roles and regulation of phospholipid scramblases.

Abstract

Phospholipid scramblase activity is involved in the collapse of phospholipid (PL) asymmetry at the plasma membrane leading to externalization of phosphatidylserine. This activity is crucial for initiation of the blood coagulation cascade and for recognition/elimination of apoptotic cells by macrophages. Efforts to identify gene products associated with this… (More)
DOI: 10.1016/j.febslet.2014.11.036

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