Role of zinc in the pathogenesis and treatment of prostate cancer: critical issues to resolve

@article{Costello2004RoleOZ,
  title={Role of zinc in the pathogenesis and treatment of prostate cancer: critical issues to resolve},
  author={Leslie C. Costello and Pei Feng and B Milon and Minjia Tan and Renty B. Franklin},
  journal={Prostate Cancer and Prostatic Diseases},
  year={2004},
  volume={7},
  pages={111-117}
}
The most consistent and persistent biochemical characteristic of prostate cancer (PCa) is the marked decrease in zinc and citrate levels in the malignant cells. This relationship provides compelling evidence that the lost ability of the malignant cells to accumulate zinc is an important factor in the development and progression of prostate malignancy. In addition, this relationship provides a rational basis for the concept that restoration of high zinc levels in malignant cells could be… CONTINUE READING
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Zinc transporters in prostate cancer.

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