Role of yolk sac endodermal cells with special reference to the fetal macrophage differentiation.

The morphological and functional characteristics of rat yolk sac endodermal cells, with particular reference to fetal macrophage (M phi) differentiation, were studied in vivo and in vitro using DA rat embryos from 8 to 16 days of gestation. At a very early stage (day 5-6) of gestation, endodermal cells are derived from proximal endoderm as an essential and… (More)