Role of xanthine oxidase in thermal injury of skin.

@article{Till1989RoleOX,
  title={Role of xanthine oxidase in thermal injury of skin.},
  author={Gerd O. Till and L S Guilds and M Mahrougui and Hans Peter Friedl and Otmar L Trentz and Peter A Ward},
  journal={The American journal of pathology},
  year={1989},
  volume={135 1},
  pages={
          195-202
        }
}
These studies were designed to assess pathophysiologic factors responsible for increased vascular permeability occurring in rat skin that has been thermally injured in vivo. Under the conditions employed, permeability changes and edema formation progressed over time, with peak changes occurring 60 minutes after thermal trauma. The plasma of thermally injured rats showed dramatic increases in levels of xanthine oxidase activity, with peak values appearing as early as 15 minutes after thermal… CONTINUE READING

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