Role of vitamin C in prevention of complex regional pain syndrome after distal radius fractures: a meta-analysis

@article{Meena2014RoleOV,
  title={Role of vitamin C in prevention of complex regional pain syndrome after distal radius fractures: a meta-analysis},
  author={Sanjay Kumar Meena and Pankaj Kumar Sharma and Shreesh Kumar Gangary and Buddhadev Chowdhury},
  journal={European Journal of Orthopaedic Surgery \& Traumatology},
  year={2014},
  volume={25},
  pages={637-641}
}
BackgroundComplex regional pain syndrome is a well-known complication after distal radius fracture with incidence ranging from 10.5 to 37 %. Some studies recommend the use of vitamin C to prevent complex regional pain syndrome. The objective of this meta-analysis was to evaluate the efficacy of vitamin C in prevention of CRPS.MethodsWe searched the PubMed, EMBASE and Cochrane library databases for randomized controlled trial (RCT) and comparative studies reporting use of vitamin C to prevent… 
The Efficacy of Vitamin C in the Prevention of Complex Regional Pain Syndrome After Distal Radius Fractures: A Synthesis
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TLDR
The analysis points to the fact that the relative efficacy of vitamin C has decreased over the past 15 years, and Vitamin C has lost its relative efficacy.
Effectiveness of prophylactic vitamin C supplementation in the prevention of complex regional pain syndrome after distal end radius fractures in the aging population
TLDR
Vitamin C (500 mg/day) supplementation was effective and associated with a lower occurrence of acute complex regional pain syndrome-1 and can be a promising prophylactic option for the prevention of complex regional Pain Syndrome-1 after distal end radius fracture.
Regional vitamin C in Bier block reduces the incidence of CRPS-1 following distal radius fracture surgery
TLDR
It is suggested that adding vitamin C 500 mg to the local anesthetic in Bier block significantly reduces the incidence of CRPS following distal radius fractures.
A meta-analysis of randomized clinical trials on the impact of oral vitamin C supplementation on first-year outcomes in orthopedic patients
TLDR
It is demonstrated that oral vitamin C supplementation may reduce the risk of complex regional pain syndrome type I but did not improve the functional outcomes in orthopedic patients.
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TLDR
The findings suggest that compared with bridging external fixation, K-wire fixation, dorsal plating, volar Plating, dorsal and volar plates, plaster fixation and non-bridging externalfix might be the better treatment methods to reduce the risk of CRPS in DRF patients.
Comparison of treatment outcomes between nonsurgical and surgical treatment of distal radius fracture in elderly: a systematic review and meta-analysis
TLDR
Surgical and nonsurgical methods produce similar results in the treatment of DRFS in the elderly, and minor objective functional differences did not result an impact on subjective function outcome and quality of life.
[Complex regional pain syndrome following distal fractures of the radius : Epidemiology, pathophysiological models, diagnostics and therapy].
TLDR
A complex interaction of inflammatory, somatosensory, motor and autonomic changes is suspected, leading to a persistent maladaptive response and sensitization of the central and peripheral nervous systems with development of the corresponding symptoms.
Influence of vitamin C on the incidence of CRPS-I after subacromial shoulder surgery
TLDR
The present study found that VC administered prophylactically for 50 days postoperatively is effective in preventing CRPS-I development after SaSS.
Serum vitamin C and spinal pain: a nationwide study
TLDR
This study shows associations between vitamin C and spinal pain that warrant further investigation to determine the possible importance of vitamin C in the treatment of back pain patients.
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TLDR
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TLDR
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