Role of vitamin C in prevention of complex regional pain syndrome after distal radius fractures: a meta-analysis

@article{Meena2014RoleOV,
  title={Role of vitamin C in prevention of complex regional pain syndrome after distal radius fractures: a meta-analysis},
  author={Sanjay Kumar Meena and Pankaj Kumar Sharma and Shreesh Kumar Gangary and Buddhadev Chowdhury},
  journal={European Journal of Orthopaedic Surgery \& Traumatology},
  year={2014},
  volume={25},
  pages={637-641}
}
BackgroundComplex regional pain syndrome is a well-known complication after distal radius fracture with incidence ranging from 10.5 to 37 %. Some studies recommend the use of vitamin C to prevent complex regional pain syndrome. The objective of this meta-analysis was to evaluate the efficacy of vitamin C in prevention of CRPS.MethodsWe searched the PubMed, EMBASE and Cochrane library databases for randomized controlled trial (RCT) and comparative studies reporting use of vitamin C to prevent… 
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The Efficacy of Vitamin C in the Prevention of Complex Regional Pain Syndrome After Distal Radius Fractures: A Synthesis
  • T. Keef, S. Keef
  • Medicine
    Journal of pain & palliative care pharmacotherapy
  • 2019
TLDR
The analysis points to the fact that the relative efficacy of vitamin C has decreased over the past 15 years, and Vitamin C has lost its relative efficacy.
Effectiveness of prophylactic vitamin C supplementation in the prevention of complex regional pain syndrome after distal end radius fractures in the aging population
TLDR
Vitamin C (500 mg/day) supplementation was effective and associated with a lower occurrence of acute complex regional pain syndrome-1 and can be a promising prophylactic option for the prevention of complex regional Pain Syndrome-1 after distal end radius fracture.
Regional vitamin C in Bier block reduces the incidence of CRPS-1 following distal radius fracture surgery
TLDR
It is suggested that adding vitamin C 500 mg to the local anesthetic in Bier block significantly reduces the incidence of CRPS following distal radius fractures.
A meta-analysis of randomized clinical trials on the impact of oral vitamin C supplementation on first-year outcomes in orthopedic patients
TLDR
It is demonstrated that oral vitamin C supplementation may reduce the risk of complex regional pain syndrome type I but did not improve the functional outcomes in orthopedic patients.
Comparison of effects of seven treatment methods for distal radius fracture on minimizing complex regional pain syndrome
TLDR
The findings suggest that compared with bridging external fixation, K-wire fixation, dorsal plating, volar Plating, dorsal and volar plates, plaster fixation and non-bridging externalfix might be the better treatment methods to reduce the risk of CRPS in DRF patients.
Comparison of treatment outcomes between nonsurgical and surgical treatment of distal radius fracture in elderly: a systematic review and meta-analysis
TLDR
Surgical and nonsurgical methods produce similar results in the treatment of DRFS in the elderly, and minor objective functional differences did not result an impact on subjective function outcome and quality of life.
[Complex regional pain syndrome following distal fractures of the radius : Epidemiology, pathophysiological models, diagnostics and therapy].
TLDR
A complex interaction of inflammatory, somatosensory, motor and autonomic changes is suspected, leading to a persistent maladaptive response and sensitization of the central and peripheral nervous systems with development of the corresponding symptoms.
Influence of vitamin C on the incidence of CRPS-I after subacromial shoulder surgery
TLDR
The present study found that VC administered prophylactically for 50 days postoperatively is effective in preventing CRPS-I development after SaSS.
Complex Regional Pain Syndrome and Distal Radius Fracture: Etiology, Diagnosis, and Treatment.
Serum vitamin C and spinal pain: a nationwide study
TLDR
This study shows associations between vitamin C and spinal pain that warrant further investigation to determine the possible importance of vitamin C in the treatment of back pain patients.
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References

SHOWING 1-10 OF 26 REFERENCES
The influence of vitamin C on the outcome of distal radial fractures: a double-blind, randomized controlled trial.
TLDR
It is concluded that administration of vitamin C confers no benefit to patients with a displaced or nondisplaced fracture of the distal aspect of the radius and there was no significant difference in the time to fracture-healing.
[Vitamin C and prevention of reflex sympathetic dystrophy following surgical management of distal radius fractures].
TLDR
A comparative study of two groups of patients with isolated closed displaced fractures of the distal radius, which were reduced and stabilized by intrafocal pinning, lends credit to the value of vitamin C administration as a prophylactic measure to prevent the occurrence of reflex sympathetic dystrophy in patients who undergo surgical treatment of a displaced fracture of thedistal radius.
Vitamine C et prévention du syndrome douloureux régional complexe de type 1 après fracture du radius distal traitée chirurgicalement.
TLDR
A comparative study of two groups of patients with isolated closed displaced fractures of the distal radius, which were reduced and stabilized by intrafocal pinning lends credit to the value of vitamin C administration as a prophylactic measure to prevent the occurrence of reflex sympathetic dystrophy in patients who undergo surgical treatment of a displaced fracture of thedistal radius.
Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures: a randomised trial
Treatment of distal radius fractures.
TLDR
The clinical practice guideline is based on a systematic review of published studies on the treatment of distal radius fractures in adults and includes surgical fixation, rather than cast fixation, for fractures with postreduction radial shortening, dorsal tilt, or intra-articular displacement or step-off.
Features of algodystrophy after Colles' fracture.
TLDR
It is concluded that algodystrophy constitutes a precisely definable and quantifiable syndrome which is more common than has been suspected and significantly associated with vasomotor instability, swelling and finger movement following Colles' fracture.
Effect of vitamin C on fracture healing in elderly Osteogenic Disorder Shionogi rats.
TLDR
The supplementary vitamin C improved the mechanical resistance of the fracture callus in elderly rats and vitamin C supplementation should be recommended during fracture healing in the elderly.
External validation of IASP diagnostic criteria for Complex Regional Pain Syndrome and proposed research diagnostic criteria
A prospective study of the intake of vitamins C and B6, and the risk of kidney stones in men.
Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up.
TLDR
The association between calcium intake and kidney stone formation varies with age and total vitamin C intake seems to increase the risk of symptomatic nephrolithiasis, and dietary recommendations for stone prevention should be tailored to the individual patient.
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