Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates.

@article{Rowe1998RoleOV,
  title={Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates.},
  author={Tony Rowe and Christopher Dascher and Sergei I Bannykh and Helen Plutner and William Edward Balch},
  journal={Science},
  year={1998},
  volume={279 5351},
  pages={696-700}
}
Syntaxins are thought to function during vesicular transport as receptors on the target membrane and to contribute to the specificity of membrane docking and fusion by interacting with vesicle-associated receptors. Here, syntaxin 5 (Syn5) was shown to be an integral component of endoplasmic reticulum-derived transport vesicles. This pool, but not the target, Golgi-associated Syn5 pool, was essential for the assembly of vesicular-tubular pre-Golgi intermediates and the delivery of cargo to the… CONTINUE READING
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