Role of ventral hippocampal nitric oxide/cGMP pathway in anxiety-related behaviors in rats submitted to the elevated T-maze

@article{Calixto2010RoleOV,
  title={Role of ventral hippocampal nitric oxide/cGMP pathway in anxiety-related behaviors in rats submitted to the elevated T-maze},
  author={A. V. Calixto and F. Duarte and M. Duzzioni and L. P. N. H{\"a}ckl and T. Lima},
  journal={Behavioural Brain Research},
  year={2010},
  volume={207},
  pages={112-117}
}
  • A. V. Calixto, F. Duarte, +2 authors T. Lima
  • Published 2010
  • Medicine, Psychology
  • Behavioural Brain Research
  • The L-arginine/nitric oxide (NO)/cGMP pathways have been implicated in the control of a variety of physiological mechanisms and are believed to participate in the modulation of anxiety in the CNS. The aim of this study was to investigate the effects of N(G)-nitro-L-arginine-methyl-ester (L-NAME), a non-selective inhibitor of NO synthase (NOS); 7-nitroindazole (7-NI), a preferential inhibitor of neuronal NOS; and sodium nitroprusside (SNP), an NO donor, administered into the ventral hippocampus… CONTINUE READING
    Hippocampus and nitric oxide.
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