Role of veins and cerebral venous pressure in disruption of the blood-brain barrier.

@article{Mayhan1986RoleOV,
  title={Role of veins and cerebral venous pressure in disruption of the blood-brain barrier.},
  author={William G Mayhan and Donald D. Heistad},
  journal={Circulation research},
  year={1986},
  volume={59 2},
  pages={216-20}
}
The goal of this study was to determine whether increases in cerebral venous pressure contribute to, and may account for, disruption of the blood-brain barrier during acute hypertension and hyperosmolar stimuli. We studied the relation between pial venous pressure and disruption of the blood-brain barrier during acute arterial hypertension, superior venae cavae occlusion, and superfusion with hyperosmolar arabinose. Sprague-Dawley rats were studied using intravital fluorescent microscopy and… CONTINUE READING