Role of vascular KATP channels in blood pressure variability after sinoaortic denervation in rats

@inproceedings{Yang2011RoleOV,
  title={Role of vascular KATP channels in blood pressure variability after sinoaortic denervation in rats},
  author={Zhong-wei Yang and Dong-jie Li and Chong Liu and Ping Han and Yi-li Yang and Ding-feng Su and Fu-ming Shen},
  booktitle={Acta Pharmacologica Sinica},
  year={2011}
}
AbstractAim:To investigate the role of ATP-sensitive potassium (KATP) channels on blood pressure variability (BPV) in sinoaortic denervated (SAD) rats.Methods:SAD was performed on male Sprague-Dawley rats 4 weeks before the study. mRNA expression of Kir6.1, Kir6.2 and SUR2 in aorta and mesenteric artery was determined using real-time quantitative polymerase chain reaction, and confirmed at the protein level using Western blotting and laser confocal immunofluorescence assays. Concentration… CONTINUE READING

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