Role of two acetylcholine receptor subunit domains in homomer formation and intersubunit recognition, as revealed by alpha 3 and alpha 7 subunit chimeras.

@article{GARCIAGUZMAN1994RoleOT,
  title={Role of two acetylcholine receptor subunit domains in homomer formation and intersubunit recognition, as revealed by alpha 3 and alpha 7 subunit chimeras.},
  author={MIGUEL GARCIA-GUZMAN and Francisco Gonz{\'a}lez Sala and Salvador Sala and Antonio Campos-Caro and Manuel Criado},
  journal={Biochemistry},
  year={1994},
  volume={33 50},
  pages={15198-203}
}
Differential expression of subunit genes from the nicotinic acetylcholine receptor (AChR) superfamily yields distinct receptor subtypes. As each AChR subtype has a specific subunit composition and many subunit combinations appear not to be expressed, each subunit must contain some information leading to proper assembly. The neuronal AChR subunits alpha 3 and alpha 7 are expressed in bovine chromaffin cells, probably as constituents of two different AChR subtypes. These subunits have different… CONTINUE READING

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