Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammals.

@article{Chen2004RoleOT,
  title={Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammals.},
  author={Qiaofang Chen and Gabriel G. Haddad},
  journal={The Journal of experimental biology},
  year={2004},
  volume={207 Pt 18},
  pages={3125-9}
}
Trehalose is a nonreducing disaccharide in which the two glucose units are linked in an alpha,alpha-1,1-glycosidic linkage. The best known and most widely distributed pathway of trehalose synthesis involves the transfer of glucose from UDP-glucose to glucose 6-phosphate to form trehalose-6-phosphate and UDP via the trehalose-6-phosphate synthase (TPS1). Trehalose-6-phosphate phosphatase (TPS2) then converts trehalose-6-phosphate to free trehalose. This sugar is present in a wide variety of… CONTINUE READING

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