Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes.

Abstract

Previous studies have suggested that the proinflammatory cytokine, TNF-alpha, contributes to airway hyperresponsivness by altering airway smooth muscle (ASM) Ca(2+) responses to agonist stimulation. The present study examined the effects of TNF-alpha on Ca(2+) influx pathways in cultured human ASM cells (HASMCs). Proteins encoded by the transient receptor… (More)

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@article{White2006RoleOT, title={Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes.}, author={Thomas A. White and Ailing Xue and Eduardo Nunes Chini and Michael A. Thompson and Gary C. Sieck and Mark E. Wylam}, journal={American journal of respiratory cell and molecular biology}, year={2006}, volume={35 2}, pages={243-51} }