Role of transforming growth factor beta3 in lymphatic metastasis in breast cancer.

@article{Li1998RoleOT,
  title={Role of transforming growth factor beta3 in lymphatic metastasis in breast cancer.},
  author={Chenggang Li and Jing Wang and Paul Wilson and P. R. Srikanta Kumar and Ellis Levine and R. Douglas Hunter and Shant Kumar},
  journal={International journal of cancer},
  year={1998},
  volume={79 5},
  pages={455-9}
}
Transforming growth factor-betas (TGFbetas) play a prominent role in tumour growth and metastasis by enhancing angiogenesis and suppressing immune surveillance. Despite the increased interest in the effect of TGFbetas on tumour progression, little is known about the importance of TGFbeta3 and its receptor CD105 in breast cancer. In the present study, we measured the plasma levels of TGFbeta3, CD105-TGFbeta3 complexes and TGFbeta1 in 80 patients with untreated early-stage breast cancer using an… CONTINUE READING

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