Role of transforming growth factor-beta in growth and injury response of the pancreatic duct epithelium in vitro

@article{Alvarez1999RoleOT,
  title={Role of transforming growth factor-beta in growth and injury response of the pancreatic duct epithelium in vitro},
  author={Carlos Alvarez and Barbara Bass},
  journal={Journal of Gastrointestinal Surgery},
  year={1999},
  volume={3},
  pages={178-184}
}
Chronic pancreatitis is characterized by increased levels of expression of transforming growth factor-beta (TGF-β), particularly in and around the ducts. To examine the consequences of elevated exposure to TGF-β on the pancreatic duct epithelium, we cultured segments of the main bovine pancreatic duct in the presence of increasing doses of TGF-β. We also… CONTINUE READING