Role of transferrin, Fe, and transferrin receptors in myeloid leukemia cell growth. Studies with an antitransferrin receptor monoclonal antibody.

@article{Taetle1985RoleOT,
  title={Role of transferrin, Fe, and transferrin receptors in myeloid leukemia cell growth. Studies with an antitransferrin receptor monoclonal antibody.},
  author={Raymond M Taetle and Kaspar Rhyner and Janice Castagnola and Dong Nguyen To and John Mendelsohn},
  journal={The Journal of clinical investigation},
  year={1985},
  volume={75 3},
  pages={1061-7}
}
In previous studies, antitransferrin receptor antibody 42/6 inhibited growth of normal granulocyte/macrophage progenitors and some malignant myeloid cells. In these studies, leukemia cell lines cultured without serum and fresh leukemia cells were used to investigate the roles of Fe, transferrin receptors, and transferrin in leukemia cell growth, and mechanisms of 42/6 inhibition and resistance. HL60 and KG-1 leukemia cells grown in serum-free medium were inhibited by 42/6. In contrast to… CONTINUE READING

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Cleavage and structural proteins during the assembly of the head of bacteriophage , T 4

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