Role of toll-like receptors 3, 4 and 7 in cellular uptake and response to titanium dioxide nanoparticles

@inproceedings{Chen2013RoleOT,
  title={Role of toll-like receptors 3, 4 and 7 in cellular uptake and response to titanium dioxide nanoparticles},
  author={Peng Chen and Koki Kanehira and Akiyoshi Taniguchi},
  booktitle={Science and technology of advanced materials},
  year={2013}
}
Innate immune response is believed to be among the earliest provisional cellular responses, and mediates the interactions between microbes and cells. Toll-like receptors (TLRs) are critical to these interactions. We hypothesize that TLRs also play an important role in interactions between nanoparticles (NPs) and cells, although little information has been reported concerning such an interaction. In this study, we investigated the role of TLR3, TLR4 and TLR7 in cellular uptake of titanium… CONTINUE READING

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