Role of thrombotic risk factors in end-stage renal disease.

  title={Role of thrombotic risk factors in end-stage renal disease.},
  author={Gaurav Tripathi and Satya Narayan Sankhwar and Raj Kumar Sharma and Vinod Pandirikkal Baburaj and Suraksha Agrawal},
  journal={Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis},
  volume={16 2},
INTRODUCTION Genetic polymorphisms that are found among factors of the coagulation cascade are factor V leiden mutation (FVL), prothrombin (PT), and methylenetetrahydrofolate reductase (MTHFR), reported for thrombotic complications. We have investigated the associations of these gene polymorphisms in patients with end-stage renal disease (ESRD). METHODS We genotyped 258 patients for FV G1691A, PT G20210A, and MTHFR (C677T, A1298C) gene by using polymerase chain reaction-restriction fragment… CONTINUE READING