Role of thrombogenic factors in the development of atherosclerosis.

@article{Marutsuka2005RoleOT,
  title={Role of thrombogenic factors in the development of atherosclerosis.},
  author={Kousuke Marutsuka and Kinta Hatakeyama and Atsushi Yamashita and Yujiro Asada},
  journal={Journal of atherosclerosis and thrombosis},
  year={2005},
  volume={12 1},
  pages={1-8}
}
Hemostatic factors play a crucial role in generating thrombotic plugs at sites of vascular damage (atherothrombosis). However, whether hemostatic factors contribute directly or indirectly to the pathogenesis of atherosclerosis remains uncertain. Autopsy studies have revealed that intimal thickening represents the first stage of atherosclerosis and that lipid-rich plaque arises from such lesions. Several factors contribute to the start of intimal thickening. Platelets release several growth… CONTINUE READING

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