Role of the thymus in tolerance. VII. Distribution of nonaggregated and heat-aggregated bovine gamma globulin in lymphoid organs of normal newborn and adult rats.


The study reported here forms an essential part of our investigations of the effect of antigen, given either systemically or directly into one of the lymphoid organs, in the induction of specific immunologic tolerance.`5 For both soluble protein and homograft systems, it has been established that tolerance induced by neonatal administration of antigen can… (More)


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